Lithium alternatives may offer a better option for addressing mood swings than you may have been presented before. Medical doctors prescribe lithium carbonate for the management of bipolar disorder and as an adjunct for major depression, however, lithium orotate and lithium aspartate can be purchased online from supplement companies. [6] The proponents of lithium orotate have since criticized the results by citing the fact that the dose of lithium orotate used in the study was in the toxic range. Lithium orotate stabilizes the lysosomal membranes and prevents the enzyme reactions that are responsible for the sodium depletion and dehydration effects of other lithium salts. Wondering if it will have any affect on DP. Books Advanced Search Amazon Charts Best Sellers & more Top New Releases Deals in Books School Books Textbooks Books Outlet Children's Books Calendars & Diaries Advanced Lithium orotate (lithium bound with a natural chemical called orotic acid, found in breast milk 7 and certain root vegetables, available as a supplement without a prescription) There have been many other compounds/mixtures produced over the last century and a half. Lithium orotate is an elemental substance that is also an essential micronutrient. Lithium orotate has the ability to potentially improve cognitive function, enhance mood, and increase bone strength. Please Read the Community Forum Guidelines Before Posting. There are two forms of lithium available to consumers: there is a natural form of the metal/mineral (lithium orotate), considered to have neuroprotective characteristics. Posted on Sep 18, 2019 in Symptoms | Comments Off on What Does Lithium Orotate Do to the Brain?. Major medical research has not been conducted on lithium orotate since the 1980s due to its patent status and the abundant availability of lithium carbonate. Lithium salts are chemical salts of lithium used mainly in the treatment of bipolar disorder as mood stabilizers. A friend of mine mentioned her anxiety has vanished since she began taking it daily, and recommended it to me. edit: I got some, going to try 5mg daily for month or two and I guess I'll report … Lithium is classified as an essential nutrient, and some of its salts are naturally found in food and drinking water. Some of the reviews on Amazon mentioned it helping Bipolar Disorder and other mental illnesses (though Im always suspicious of Amazon reviews). Lithium compounds, also known as lithium salts, are primarily used as a psychiatric medication. It is possible that certain formats are more effective and/or safer than others in the specific domain of anxiety disorders. Noncontrolled studies have examined the use of low-dose lithium orotate in the treatment of alcoholism, migraines, and depression associated with bipolar disorder. In this compound, lithium is non-covalently bound to an orotate ion, rather than to a carbonate or other ion, and like other salts, dissociates in solution to produce free lithium … They are also sometimes used to treat depression and mania. By continuing to browse our site you agree to our use of data and cookies. Mechanism unknown according to google. I read on another forum someone taking lithtium orotate and claims it helped reduce their DP with 60% so I'm going to try it. Only thing I have issues with are hand shakes and slight tremors in the morning. Lithium Orotate Compared to Other Lithium Salts Relentless Improvement Lithium Orotate is well priced and it works. I think they are one in the same though, somehow. H 2 O. The orotate form of lithium is used by doctors to help stabilize and equilibrate mood. It has also been known to be used to manage depression, mental health issues, and alcoholism.Let us look at the benefits in detail. Although lithium orotate is considered safer than other lithium-based compounds, there are still a number of side effects, drug interactions and potentially serious conditions that can result from regular lithium orotate use 1 3. J Pharm Pharmacol 1979;31:161-3.. View abstract. Available in dietary supplement form, lithium orotate is touted as a natural treatment for a wide range of mental health problems. Furthermore, the 24 h brain concentration of lithium after lithium orotate was approximately three times greater than that after lithium carbonate. [14], InChI=1S/C5H4N2O4.Li/c8-3-1-2(4(9)10)6-5(11)7-3;/h1H,(H,9,10)(H2,6,7,8,11);/q;+1/p-1, "The clinical applications of lithium orotate. Lithium Orotate at low doses is non-toxic and lab tests are not required to monitor your lithium levels because it does not show up in blood samples. A friend of mine mentioned her anxiety has vanished since she began taking it daily, and recommended it to me. I don't think it had any beneficial effect. Lithium Orotate seems to come in 120mg capsules, most often, but it's confusing because people often say they only take 5 to 10 mg daily. It supposedly controls mood swings. Lithium calms mania and mood swings by decreasing the sensitivity of norepinephrine receptors. Lithium orotate dosage depends on the condition that is being treated. Lithium Orotate should not be used if you are dealing with significant renal or cardiovascular disease, severe dehydration or sodium depletion, or if you’re taking diuretics or ACE inhibitors. A two years study", "Lithium orotate, carbonate, and chloride: pharmacokinetics, polydipsia and polyuria in rats", "Lithium toxicity from an Internet dietary supplement", "Vitamin B13 cannot be proven safe, says EFSA", https://en.wikipedia.org/w/index.php?title=Lithium_orotate&oldid=963440355, Articles with changed ChemSpider identifier, Chemical pages without DrugBank identifier, Drugboxes which contain changes to verified fields, Drugboxes which contain changes to watched fields, Creative Commons Attribution-ShareAlike License, This page was last edited on 19 June 2020, at 20:28. And there is its synthesized counterpart (lithium carbonate). Please re-enable javascript to access full functionality. I can actually think straight now, my depersonalisation has decreased by 60% anxiety by about 30% and my memory and recall has drastically improved. FREE Shipping on orders over $25 shipped by Amazon. There was a woman on 120mg of lithium orotate who went toxic after 22 days (just read the article earlier today, sorry lost the link, I was doing personal research, as I am asking myself the same question about orotate, and having difficulties finding the answers I need). It lithium-orotate and lithium-carbonate behave differently, they are both well absorbed from the intestines but lithium from lithium-orotate seems to be better absorbed into the cells of the body, it has also been shown to be more slowly excreted by the kidneys so it is retained in the body for a longer period of time compared to lithium from lithium-carbonate [insert ref]. Lithium is taken by mouth. 0 m equiv kg−1 lithium carbonate, two‐thirds of the 2 h serum lithium concentration was present 24 h after lithium orotate. This, along with L-theanine, has greatly reduced my anxiety, depression, agitation, repetitive thoughts and helps me sleep. 5.0 out of 5 stars 1. Nieper HA The curative effect of a combination of Calcium-orotate and Lithium orotate on primary and secondary chronic hepatitis and primary and secondary liver cirrhosis. Lithium Orotate - posted in Treatment Options: Wondering if anybody out there has experience with this supplement. In this compound, lithium is non-covalently bound to an orotate ion, rather than to a carbonate or other ion, and like other salts, dissociates in solution to produce free lithium ions. The only negative thing I have to say is, the tablet is larger than the other brand I've tried. Lithium is an element. Lithium’s Mechanism of Action: An Illustrated Review, This is not recommended for shared computers. Concerns have been raised in medical literature after a case report of a patient who required medical attention after taking an overdose of lithium orotate supplement. Online shopping from a great selection at Books Store. 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